ncRNA name | ephrinB2 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Macaca mulatta |
Tissues/Cell_line | rhesus choroid-retinal endothelial cell line RF/6A |
Methods | tube formation assay, EdU incorporation assay, transwell assay, DAPI staining, siRNA transfection, high-performance liquid chromatography (HPLC), qRT-PCR, Western blot |
Expression pattern | associated |
Functional description | ADMA contributes to the neovascularization of retina in diabetic mellitus. The angiogenic effects of ADMA were blocked by ephrinB2 siRNA. |
PubMed ID | 29777874 |
Year | 2018 |
Title | Asymmetric dimethylarginine contributes to retinal neovascularization of diabetic retinopathy through EphrinB2 pathway. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.